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    600+ participants
    50+ investigators
    13+ clinical sites
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The Ontario Neurodegenerative Disease Research Initiative (ONDRI) is a provincial collaboration studying dementia and how to improve the diagnosis and treatment of neurodegenerative diseases including:

  • Alzheimer’s disease
  • Parkinson’s disease
  • amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease)
  • frontotemporal lobar degeneration
  • vascular cognitive impairment (resulting from stroke)

About us

600+ participants
50+ core investigators (clinicians and researchers)
13+ clinical sites
4 patient advocacy groups
industrial partners

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Dementia is the single greatest cause of disability and debilitation in Canada’s senior population. It costs Canadians billions of dollars per year – a figure expected to grow tenfold over the next 20 years including a tenfold increase in demand for long-term care.

Disease-modifying interventions are needed now to alter these alarming trends.

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Our mandate is to ensure that the findings from the data collected are transformed into new diagnostic methods that will help detect diseases earlier, improved clinical practice that puts patients first, and eventually new effective treatments that will slow the diseases from progressing or even prevent the disease so people can continue to enjoy the later years of their lives.

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Enrollment closed on March 31, 2017 with 500 participants.


See enrollment by location and disease