Comparison of Diffusion Tensor Imaging Metrics in Normal-Appearing White Matter to Cerebrovascular Lesions and Correlation with Cerebrovascular Disease Risk Factors and Severity

October 2022
Journal: International Journal of Biomedical Imaging
Lead Author: Seyyed M H Haddad

All Authors: Seyyed M H Haddad, Christopher J M Scott, Miracle Ozzoude, Courtney Berezuk, Melissa Holmes, Sabrina Adamo, Joel Ramirez, Stephen R Arnott, Nuwan D Nanayakkara, Malcolm Binns, Derek Beaton, Wendy Lou, Kelly Sunderland, Sujeevini Sujanthan, Jane Lawrence, Donna Kwan, Brian Tan6, Leanne Casaubon, Jennifer Mandzia, Demetrios Sahlas, Gustavo Saposnik, Ayman Hassan, Brian Levine, Paula McLaughlin, J B Orange, Angela Roberts, Angela Troyer, Sandra E Black, Dar Dowlatshahi, Stephen C Strother, Richard H Swartz, Sean Symons, Manuel Montero-Odasso, Ondri Investigators, Robert Bartha


This study demonstrated the differences between conventional DTI metrics, FA, MD, AD, and RD, in cerebral vascular lesions and healthy tissue types. Therefore, incorporating DTI to characterize the integrity of the tissue microstructure could help to define the extent and severity of various brain vascular anomalies.