AIM 4: Health Services Research and Knowledge Translation 

Catalyze health services research, system evaluation, knowledge translation and system interventions to improve the health and well-being of Ontarians with neurodegenerative disease.

This platform will:

  • Utilize the ICES health administrative data repository to characterize the health services utilization and outcomes of persons with neurodegenerative diseases. 
  • Develop methods for case identification using administrative data 
  • Facilitate pragmatic clinical trials and innovative clinical trial designs 
  • Inform clinical pratice and heatlh care funding policy 
  • Strengthen linkages between Brain-CODE and ICES 
Research Questions

Amyotrophic Lateral Sclerosis

  • What care do individuals receive prior to being diagnosed with ALS? Does it differ between individuals who reside in urban and rural regions? 

Parkinson’s disease

  • Is previous use of a potentially disease modifying drug associated with the risk of Parkinson’s disease?
  • Does the incidence and prevalence of Parkinson’s disease differ between urban and rural regions in Ontario?

Vascular Cognitive Impairment

Do men and women who have had a stroke:

  • Receive different health care services prior to entering a long-term care home?
  • Have different levels of care needs and survival after entering long-term care?

Alzheimer’s and related dementias

  • How do persons with dementia utilize the health system as they remain in the community over time?

Neurodegenerative Multimorbidity

  • What is the risk of having two or more “comorbid” neurodegenerative and mental health conditions?