AIM 4: Health Services Research and Knowledge Translation 

Catalyze health services research, system evaluation, knowledge translation and system interventions to improve the health and well-being of Ontarians with neurodegenerative disease.

The ONDRI health services research platform uses “big” databases to better understand the health status and outcomes of persons with neurodegenerative diseases in Ontario. By using a large repository of health data routinely captured during visits to family doctors, specialists, and during hospitalizations and other health system encounters, the ONDRI health services research platform can better understand how persons with neurodegenerative diseases access the health system, how their health status changes over time, which medications they use and how these impact health, and what opportunities for improvement exist in the areas of clinical care and health system access. This information will be useful for health system planners and other stakeholders when planning to meet the health care needs of persons with neurodegenerative diseases, now and in the future.

Research Questions

Amyotrophic Lateral Sclerosis

  • Do men and women with ALS receive different health care services prior to diagnosis?

Parkinson’s disease

  • What are the patterns of “Watson drug” use in persons with and without Parkinson’s disease?
  • Is previous use of a “Watson drug” associated with the risk of Parkinson’s disease?

Vascular Cognitive Impairment

  • Do men and women who have had a stroke:
  • Receive different health care services prior to entering a long-term care home?
  • Have different levels of care needs and survival?

Alzheimer’s and related dementias

  • How do persons with dementia utilize the health system as they remain in the community over time?

Neurodegenerative Multimorbidity

  • What is the risk of having two or more “comorbid” neurodegenerative and mental health conditions?