ONDRI Publications

Parkinson’s Disease, NOTCH3 Genetic Variants, and White Matter Hyperintensities

June 2020

Journal: Movement Disorders

Co-Lead Authors: Joel Ramirez and Allison A. Dilliott

This novel research that examined MRI from Parkinson’s disease patients, found that brain lesions from damage to small blood vessels may be due to rare changes within the NOTCH3 gene.

Abstract link.  

Learn more about the background of this publication here. 

ONDRI Publications

Below you will find a list of publications from work that has been supported by ONDRI and the Ontario Brain Institute.

Each title is linked to its PubMed listing and abstract or, if the article is open-access, to the article itself. 

Ontario Neurodegenerative Disease Research Initiative (ONDRI): Structural MRI Methods and Outcome Measures

August 2020 

Journal: Frontiers in Neurology 

Lead Author: Joel Ramirez

Article link. 

Trajectories of health system use and survival for community-dwelling persons with dementia: a cohort study

July 2020 

Journal: BMJ Journal

Lead Author: Susan E. Bronskill 

Article link. 

Methods for Improving Screening for Vascular Cognitive Impairment Using the Montreal Cognitive Assessment

June 2020

Journal: Canadian Journal of Neurological Sciences 

Lead Author: KB Zaidi

Abstract link. 

Parkinson's Disease, NOTCH3 Genetic Variants, and White Matter Hyperintensities

June 2020

Journal: Movement Disorders

Lead Author: Joel Ramirez

Abstract link. 

 

The Quality Assurance and Quality Control Protocol for Neuropsychological Data Collection and Curation in the Ontario Neurodegenerative Disease Research Initiative (ONDRI) Study

May 2020 

Journal: SAGE Journals 

Lead Author: Paula M. McLaughlin 

Abstract link. 

Identifying drugs with disease‐modifying potential in Parkinson's disease using artificial intelligence and pharmacoepidemiology

May 2020 

Journal: PDS Pharmacoepidemiology & Drug Safety

Lead Authors: Laura C. Maclagan, Naomi P. Visanji

Abstract link. 

Structural Brain Magnetic Resonance Imaging to Rule Out Comorbid Pathology in the Assessment of Alzheimer’s Disease Dementia: Findings from the Ontario Neurodegenerative Disease Research Initiative (ONDRI) Study and Clinical Trials Over the Past 10 Years

February 2020  

Journal: Journal of Alzheimer’s Disease 

Lead Author: Arumina Kapoor  

Article link. 

Sex Differences in Care Need and Survival in Patients Admitted to Nursing Home Poststroke

January 2020  

Journal: The Canadian Journal of Neurological Sciences

Lead Author: Amy Y. X. Yu 

Abstract link. 

Comparison of quality control methods for automated diffusion tensor imaging analysis pipelines

January 2020 

Journal: PLOS One 

Lead Author: Seyyed M. H. Mohammed  

Article link. 

Validation of Optical Coherence Tomography Retinal Segmentation in Neurodegenerative Disease

September 2019 

Journal: ARVO International

Lead Author: Bryan M Wong 

Article link. 

Genetic Variation in the Ontario Neurodegenerative Disease Research Initiative

September 2019 

Journal: The Canadian Journal of Neurological Sciences

Lead Author: Allison A Dilliott 

Article link. 

The Utility of multivariate outlier detection techniques for data quality evaluation in large studies: an application within the ONDRI Project

May 2019 

Journal: BMC Medical Research Methodology 

Lead Author: Kelly M Sunderland 

Article link.

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

April 2018

Journal: Journal of Visualized Experiments 

Lead Author: Allison A Dilliott

Article link. 

Brain-CODE: A Secure Neuroinformatics Platform for Management, Federation, Sharing and Analysis of Multi-Dimensional Neuroscience Data

May 2018 

Journal: Frontiers In Neuroinformatics

Lead Author: Anthony L. Vaccarino 

Article link.

Motor Phenotype in Neurodegenerative Disorders: Gait and Balance Platform Study Design Protocol for the Ontario Neurodegenerative Research Initiative (ONDRI).

July 2017 

Journal: Journal of Alzheimer’s Disease

Lead Author: Manuel Montero-Odasso 

Article link. 

The Ontario Neurodegenerative Disease Research Initiative (ONDRI)

March 2017 

Journal: Canadian Journal of Neurological Sciences

Lead Author: Sali M K Farhan 

Article link. 

The ONDRISeq panel: custom-designed next-generation sequencing of genes related to neurodegeneration

September 2016 

Journal: npj Genomic Medicine  

Lead Authors: Sali M K Farhan, Allison A Dilliott

Article link.