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Structural Brain Magnetic Resonance Imaging to Rule Out Comorbid Pathology in the Assessment of Alzheimer’s Disease Dementia: Findings from the Ontario Neurodegenerative Disease Research Initiative (ONDRI) Study and Clinical Trials Over the Past 10 Years

February 2020 
Journal: IOS Press
Lead Author: Arumina Kapoor

All Authors: Arumina Kapoor, Robert Bartha, Sandra E. Black, Micheal Borrie, Morris Freedman, Fugiang Gao, Nathan Herrmann, Jennifer Mandzia, Miracle Ozzoude, Joel Ramire, Christopher J.M. Scott, Sean Symons, Corinne Fischer, Andrew Frank, Dallas Seitz, Michael Uri Wolf, Nicolaas Paul L.G. Verhoeff, Gary Naglie, William Reichman, Mario Masellis, Sara B. Mitchell, David F. Tang-Wai, Maria Carmela Tartaglia, Suneev Kumar, Bruce G. Pollock, Tarek K. Raijj, Elizabeth Finger, Stephen H. Pasernak, Richard H. Swartz

Dementia is often the result of overlapping diseases. This research shows the importance of using brain MRI’s routinely in clinical trials to account for the impact of co-morbid conditions.